临床兽医学系

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  • 高文文副教授
  • 性别:女
  • 职称:副教授
  • 硕导/博导:博导
  • 学科专业:临床兽医学
  • 最高学位:博士
  • 研究方向:动物营养代谢病
  • 最高学历:研究生
  • 邮箱:gaowenwen@jlu.edu.cn

讲授课程

本科生:兽医临床病理学

动物营养代谢病与中毒病

专业英语

教育经历

(1)2016-09至2020-09,法国巴黎大学,药理学,博士

(2)2013-09至2016-06,全讯600cc大白菜,临床兽医学,硕士

(3)2009-09至2013-06,锦州医科大学,临床兽医学,学士

工作经历

2021-09至今,全讯600cc大白菜,2024白菜网址官网大全,副教授

科研项目

(1)全讯600cc大白菜人才引进科研启动基金,29万。

(2)国家自然科学基金委员会,青年科学基金项目,32302941,高NEFA血症激活IRE1α-RIDD介导酮病奶牛乳腺上皮细胞凋亡的机制,2024-01-01至2026-12-31,30万元,在研,主持

(3)吉林省教育厅,2023年度吉林省教育厅科学研究项目,JJKH20231203KJ,Caspase 12调控酮病奶牛乳腺上皮细胞凋亡损伤的作用机制,2023-01至2024-12,2.5万元,在研,主持

(4)吉林省科学技术厅,青年成长科技计划项目,20220508053RC,PHB2(prohibitin2)介导的线粒体自噬在酮病奶牛乳腺凋亡损伤的作用机制,2022-07至2024-06,12万元,在研,主持

(5)重庆市科学技术局,重庆市自然基金面上项目,CSTB2023NSCQ-MSX0869,Caspase 6介导呕吐毒素和伏马毒素B1联合导致奶牛乳腺上皮细胞凋亡的机制研究,2023-07至2026-06,10万元,在研,主持

(6)中华人民共和国科学技术部,“十四五”国家重点研发计划子课题,2023YFD1301002,饲料饲草真菌毒素联合毒性效应的精准评估及其降解剂安全有效性评价,2023-12至2028-11,50万元,在研,主持

学术论文

(1)Wenwen Gao; Lei Liu; Eunna Huh; Florence Gbahou; Erika Cecon; Masaya Oshima; Ludivine Houzé; Panagiotis Katsonis; Alan Hegron; Zhiran Fan; Guofei Hou; Guillaume Charpentier; Mathilde Boissel; Mehdi Derhourhi; Michel Marre; Beverley Balkau; Philippe Froguel; Raphael Scharfmann; Olivier Lichtarge; Julie Dam; Amélie Bonnefond; Jianfeng Liu & Ralf Jockers; Human GLP1R variants affecting GLP1R cell surface expression are associated with impaired glucose control and increased adiposity,Nature Metabolism, 2023, 5(10):1673-1684.

(2)Wenwen Gao;Yanxi Wang; Siyu Liu; Guojin Li; Qi Shao; Cai Zhang; Liguang Cao; Kai Liu; Wenrui Gao;Zifeng Yang; Yifei Dong; Xiliang Du; Lin Lei; Guowen Liu; and Xinwei Li; IRE1α-JNK axis activation contributes to intracellular lipid accumulation in calf hepatocytes,Journal of Dairy Science, 2023.

(3)Wenwen Gao; Zhiyuan Fang; Lin Lei; Lingxue Ju; Bo Jin; Juan J. Loor; Yusheng Liang; Zhen Shi; Taiyu Shen; Hao Yu; Meng Chen; Hongsheng Ouyang; Yuxiang Song; Zhe Wang; Guowen Liu; Xinwei Li; Xiliang Du; Propionate alleviates palmitic acid–induced endoplasmic reticulum stress by enhancing autophagy in calf hepatic cells,Journal of dairy science, 2021, 104(8): 9316-9326.

(4) Zhen Shi; Yuxiang Song; Xinxing Gao; Juan J. Loor; Ahmad Aboragah; Hao Yu; Zhiyuan Fang; Yiwei Zhu; Xiliang Du; Xinwei Li;Wenwen Gao; Guowen Liu; Disruption of endoplasmic reticulum homeostasis exacerbates liver injury in clinically ketotic cows,Journal of dairy science, 2021,104(8): 9130-9141.

(5)Wenwen Gao; Ralf Jockers ; Pharmacogenomics of GPCR genes in type 2 diabetes and obesity,Current Opinion in Endocrine and Metabolic Research, 2020, 16(16): 128-135.

(6) Minghe Fan; Xiliang Du; Xiying Chen; Hongxu Bai; Juan J. Loor; Taiyu Shen; Yusheng Liang;Xudong Sun; Qiushi Xu; Yuxiang Song; Zhe Wang; Guowen Liu; Liangyu Yang; Xinwei Li; Xiaobing Li;Wenwen Gao; Inhibition of cell death inducing DNA fragmentation factor-α-like effector c (CIDEC) by tumor necrosis factor-α induces lipolysis and inflammation in calf adipocytes,Journal of dairy science, 2020, 104(05): 6134-6145.

(7)Wenwen Gao; Xiliang Du; Lin Lei; Heyuan Wang; Min Zhang; Zhe Wang; Xiaobing Li; Guowen Liu; Xinwei Li; NEFA-induced ROS impaired insulin signalling through the JNK and p38MAPK pathways in non-alcoholic steatohepatitis,Journal of Cellular and Molecular Medicine, 2018, 22(7): 3408-3422.

社会兼职

中国畜牧兽医学会兽医内科与临床诊疗学分会理事

联系我们

学院电话:0431-87836150

动物医院电话:0431-87836297 或 87836298

地址:全讯600cc大白菜 - 2024白菜网址官网大全